Juvederm gel
family of products is a hyaluronic acid
dermal filler that provide a smooth, long-lasting
correction of facial wrinkles and folds. Its
formulations result in a smooth, natural look and contain
the highest concentration of non-animal and cross-linked
hyaluronic acid of any dermal filler currently available.
These unique attributes provide optimal results with a
single treatment in the majority of patients and deliver
sustained results for up to six months or longer.
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The product is
made by the same company that makes
Botox
- Allergan. It is natural, biodegradable and currently the
only approved hyaluronic acid dermal filler that has
demonstrated its safety and effectiveness in patients of
all skin types and colors. It also is the only product is
a malleable smooth gel that flows easily into the skin,
creating a smooth, natural look and feel. All other
products utilize a gel particle suspension formulation
that can be seen as opposed to the smoother formulation
used in Juvederm.
Another
benefit of this
injectable is that the majority of patients do not
require touch-ups following their initial treatment. The
smooth consistency also may help to minimize the
discomfort that can sometimes occur during the injection
procedure. The FDA has approved three different
formulations for Juvederm providing physicians with the
flexibility to tailor each treatment to the particular
needs of the patient. (Related:
Revanesse) |
Hyaluronic
acid is a natural complex sugar found in all
living organisms and
creates volume and elasticity in the skin.
Juvederm adds volume to facial wrinkles, such as
nasolabial folds (the folds running from the sides
of the bottom of the nose to the outer corners of
the mouth).
Botox works differently -- by relaxing the
dominant frown muscles between the eyebrows (the
glabellar area). This allows the two vertical
lines between the brows, often referred to as the
"11," to temporarily diminish in appearance. Like
Botox, which has been available for more than 16
years and is currently approved to treat 20
different medical conditions in more than 75
countries around the world, hyaluronic acid treats
multiple medical conditions, including those
associated with the eye and the knee, and has been
used for more than 20 years.
Physicians
often will use a combination of products to obtain a
desired
facial rejuvenation look that is natural, expressive
and fresh. Allergan manufactures some of them, for example
the only
collagen-based dermal fillers (non-animal based
CosmoDerm and CosmoPlast that require no prior allergy
testing; and physician-dispensed products such as
PREVAGE MD.Risks and
safety
In clinical
studies, Juvederm was found to provide a more persistent
wrinkle correction than
Zyplast over the 6-month course of the study. In
addition, among non-Caucasian patients (all Fitzpatrick
Skin Types), it was found safe and effective and
demonstrated no increased risk of
hyperpigmentation or hypertrophic scarring. Side
effects, however, were usually mild to moderate in nature,
did not require intervention and lasted seven days or
less. The most common side effects included temporary
injection site reactions including redness,
pain/tenderness, firmness, swelling, lumps, and bumps and
bruising.
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